Pacira Pharmaceuticals
10450 Science Center Drive
San Diego, CA 92121
(858) 625 2424
5 Sylvan Way
Parsippany, NJ 07054
(973) 254 3560
DepoDur® is a sustained-release, injectable morphine sulfate indicated for the relief of postsurgical pain. One epidural injection at the lumbar level provides effective pain relief of up to 48 hours. DepoDur has demonstrated improved mobility and freedom from indwelling catheters.
In clinical trials, the majority of adverse events reported were typical opioid-related side effects, expected in the surgical populations studied. As with all opioids, the most serious side effect of morphine sulfate is respiratory depression, especially in elderly and debilitated patients, and in those with compromised respiratory function. The most common adverse events (greater than 10%) were decreased oxygen saturation, hypotension, urinary retention, vomiting, constipation, nausea, pruritus, pyrexia, anemia, headache, and dizziness.