Overreliance on opioids in the postsurgical setting has set off a cascade of negative consequences, ranging from potentially severe adverse events to the risk of long-term use, misuse, and addiction.Why we push for change
Redefining pain management
Our long-acting local analgesic, EXPAREL® (bupivacaine liposome injectable suspension), is a non-opioid medication administered at the time of surgery to control pain while reducing opioid* requirements.
EXPAREL combines bupivacaine with the DepoFoam® drug delivery platform to provide long-lasting postsurgical pain control when administered via infiltration, field block, or interscalene brachial plexus nerve block.
Our iovera⁰ system is an FDA-approved handheld cryoanalgesia device used to deliver precise, controlled doses of cold temperature only to targeted nerves, interrupting the nerve’s ability to transmit a pain signal. Results can be felt immediately after iovera⁰ treatment with pain relief that can last three months, and in some cases longer, as the nerve regenerates over time.
The iovera⁰ system offers a non-opioid solution for the management of pain associated with both orthopedic surgery and persistent orthopedic conditions such as osteoarthritis.Our innovative, opioid-free alternatives
*The clinical benefit of the decrease in opioid consumption was not demonstrated in the pivotal trials.