Advancing
patient care

Overreliance on opioids in the postsurgical setting has set off a cascade of negative consequences, ranging from potentially severe adverse events to the risk of long-term use, misuse, and addiction.

Why we push for change

Redefining pain management

Our long-acting local analgesic, EXPAREL® (bupivacaine liposome injectable suspension), is a non-opioid medication administered at the time of surgery to control pain while reducing opioid* requirements.

EXPAREL combines bupivacaine with the DepoFoam® drug delivery platform to provide long-lasting postsurgical pain control when administered via infiltration, field block, or interscalene brachial plexus nerve block.

Our iovera system is an FDA-approved handheld cryoanalgesia device used to deliver precise, controlled doses of cold temperature only to targeted nerves, interrupting the nerve’s ability to transmit a pain signal. Results can be felt immediately after iovera treatment with pain relief that can last three months, and in some cases longer, as the nerve regenerates over time.

The iovera system offers a non-opioid solution for the management of pain associated with both orthopedic surgery and persistent orthopedic conditions such as osteoarthritis.

Our innovative, opioid-free alternatives

*The clinical benefit of the decrease in opioid consumption was not demonstrated in the pivotal trials.